Midi-chlorian manipulation

"Is it possible to learn this power?" "Not from a Jedi."

- Anakin Skywalker and Palpatine

Midichlorian Manipulation was form of Sith Alchemy allegedly mastered by Darth Plagueis. Requiring immense knowledge of the dark side of the Force, it was the ability to create, maintain, or save life through the influencing of midi-chlorians to a certain degree

Darth Plagueis stated that a child born of this power would be the embodiment of the Force. Later, Palpatine used the promise of this power's affects to entice Anakin Skywalker further to the dark side.

It is also possible that Darth Sion used this power to keep himself alive.

Appearances

 * Tag & Bink: Revenge of the Clone Menace
 * Star Wars Episode III: Revenge of the Sith
 * Dark Lord: The Rise of Darth Vader
 * Star Wars: Knights of the Old Republic II: The Sith Lords