The Corellian Trade Spine was a major trade route. It began at Corellia and headed towards the edge of the galaxy, in the direction of Duro. It passed Devaron and Bestine before intersecting the Rimma Trade Route at Yag'Dhul. As it continued it passed through the Greater Javin region of space (which contains the Ison Trade Corridor) before intersecting the Hydian Way and exiting into open inter-galactic space.
The Corellian Trade Spine was established prior to 5,500 BBY. It was built incrementally over the centuries. Most of the outer spine beyond Yag'Dhul was relatively new, with parts having been opened only within the last few centuries BBY by Ecclessis Figg.