- "Hold it right there! You're not going anywhere, bounty hunter."
- ―Denal, to Cad Bane
In the early months of the Clone Wars, Denal was placed in Clone Captain CT-7567's squad of the 501st Legion under Jedi General Anakin Skywalker's and Ahsoka Tano's command. After transferring from the 327th Star Corps. 
First Battle of Geonosis Edit
Denal faced his first trial of combat like many other clones on Geonosis he fought alongside captain rex and made himself well known for his out of the box thinking and soon promoted to lieutenant wearing the iconic green markings from Episode II. Later he styled his own armour and became Rex's right hand man.
When Skywalker's personal astromech droid, R2-D2, was held captive by the scavenger Gha Nachkt and scheduled to be handed over to General Grievous at Skytop Station, Denal was assigned to be a part of the rescue squad to save the R2 unit and destroy the Separatist spy station. During this mission, he, Commander Tano, and the rest of the squad were attacked by General Grievous. He and Rex were the only survivors of Grievous's attack.
After planting the bombs, Denal and Rex met up with Skywalker and R2 in the station's landing bay. However, they were then trapped there by R3-S6, who revealed himself to be a Separatist spy. They then came under attack by super battle droids and vulture droids. After setting off the explosions, Denal, Rex, Skywalker, and Ahsoka were able to board the Twilight before the station was destroyed.
Battle of DevaronEdit
Denal was sent with Skywalker, Tano, and Rex to Devaron to stop bounty hunter Cad Bane from acquiring the Kyber memory crystal from Master Bolla Ropal on Devaron. He and the others then boarded Bane's command ship. There, they fought Bane and his battle droids. After fighting the battle droids to acquire a Sheathipede-class transport shuttle, Denal and Koho were then sent by Rex to find Skywalker and Tano. They then found Bane and held him up, threatening them. However, Bane overpowered them, killing both Koho and Denal.
Bane switched armor with Denal, and faked his death. At first, the clone troopers were impressed with Denal's apparent killing of Bane. However, Bane's disguise was uncovered by one of the clones who saw the Duros' blood, and Ahsoka, who discovered that "Denal" was Bane after following him from the shuttle. Bane then made his escape in a V-19 torrent starfighter.