Drethi were winged beasts bred to kill Jedi. The Drethi produced a venom which "burns when the Force flows," making its lethality commensurate with the victim's contact with the Force. The Jedi Padawan, Niquon, fought a Drethi on Skalokor when facing a group of Dark Jedi who had rediscovered the ancient beasts. There was an audible sizzling sound when a Jedi's wounds were touched with Drethi venom. The poison was absolutely lethal to a Jedi unless an antidote made from the venom itself was administered immediately. When a Drethi was killed, it disintegrated into black ash.

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