- "Small, huh? Don't worry, Supreme Leader, we'll take care of him."
- ―A B1-series battle droid, to Asajj Ventress
Supreme Leader was a military title used by Asajj Ventress, a Force-sensitive assassin who served as a commander in the Separatist Droid Army of the Confederacy of Independent Systems during the Clone Wars. During her time as Supreme Leader, Ventress deployed a battalion of battle droids against Yoda in an effort to kill the Grand Master of the Jedi Order. However, Yoda defeated the Separatist droids with the help of the diplomatic service clone troopers and confronted Ventress in person, causing the Supreme Leader to flee from Rugosa.
- Star Wars: The Clone Wars – "Ambush" (First appearance)
- "Sharing the Same Face"—The Clone Wars: Stories of Light and Dark