During the early stages of the Galactic Empire's reign, the Inquisitorius, a special unit of Jedi hunters led by the Sith Lord Darth Vader, utilized a Zeta-class shuttle, the Infernum, during a mission to Mon Cala to hunt a probable Jedi advisor, revealed to be the former Padawan Ferren Barr, to the King of Mon Cala. The shuttle was later destroyed when Mon Calamari King Lee-Char ordered the destruction of all the surface cities on Mon Cala, including Dac City.
Years later, Vader, along with Fifth Brother, a Twi'lek Inquisitor and another Inquisitor, used a Zeta-class shuttle to return to Coruscant after hunting down and killing former Jedi Master Eeth Koth.
Three Zeta-class shuttles were also carried aboard the Strikefast, a Venator-class Star Destroyer commanded by Captain Voss Parck. The Chiss military commander Thrawn infiltrated the Strikefast and was cornered aboard one of the shuttles before willingly surrendering himself.
- Darth Vader: Dark Lord of the Sith 13: Burning Seas, Part I (First pictured)
- Darth Vader: Dark Lord of the Sith 14: Burning Seas, Part II
- Darth Vader: Dark Lord of the Sith 19: Fortress Vader, Part I
- Thrawn (First appearance)